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30-Minute Workout Boosts Mood, Fights Depression: Study

11/24/2025

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Story summary
  • A study published in Molecular Psychiatry finds that one thirty-minute session of physical activity provides immediate antidepressant effects in humans and mice.
  • The research identifies adiponectin, a hormone released by fat cells, that enhances brain plasticity and mood.
  • In human trials, participants reported improved mood after exercise, supporting its potential to prevent depression.
  • In mouse models, exercise activated glutamatergic neurons in the anterior cingulate cortex.