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Story summary
- A recent study shows the protein PON3 reduces delirium risk and is linked to lipid metabolism.
- The study suggests potential for PON3-targeted drugs, particularly in relation to statin use, and monitoring APOE status and PON3 protein levels could help identify patients at higher risk before hospital admissions.
- Genetic factors such as the APOE ?4 gene, combined with inflammation, may increase brain vulnerability during acute stress from surgery or illness.
