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NFL Week 13 Preview: Arizona Cardinals vs. Tampa Bay Buccaneers

11/27/2025, 12:22:43 PM

Matchup Overview

The Arizona Cardinals (3-8) are set to face the Tampa Bay Buccaneers (6-5) at Raymond James Stadium in Tampa for their Week 13 matchup on November 30, 2025. This game is crucial for both teams, with the Buccaneers aiming to end a three-game losing streak and the Cardinals looking to improve their dismal season record.

Injury Reports and Player Updates

Both teams are dealing with significant injuries. The Cardinals have ruled out several players, including Kelvin Beachum (groin) and Walter Nolen (knee). Notably, running back Trey Benson is still recovering from a knee injury, and his status remains uncertain as he has not yet been activated from injured reserve. Meanwhile, the Buccaneers are monitoring quarterback Baker Mayfield, who suffered a low-grade AC joint sprain in Week 12. Mayfield's participation in practice has been limited, and backup Teddy Bridgewater is preparing to take the majority of first-team reps.

Key Player Performances

The Cardinals have struggled offensively, particularly in the running game, ranking 25th in the NFL. They recently signed running back Montrell Johnson Jr. to their practice squad to bolster their depth. Johnson, a rookie out of Florida, adds to a backfield that has been depleted due to injuries. The Cardinals' passing game has seen a rise in production from wide receiver Michael Wilson, who has recorded 25 catches for 303 yards over the last two games. However, the return of Marvin Harrison Jr. from appendicitis could impact Wilson's target share.

For the Buccaneers, Mayfield's potential absence raises questions about their offensive strategy. If Mayfield cannot play, Bridgewater will step in, and the Buccaneers will need to adapt their game plan accordingly. The Buccaneers' defense has struggled recently, allowing the seventh-most passing yards per game, which could provide an opportunity for the Cardinals' aerial attack.

Betting Odds and Predictions

The opening betting lines favor the Buccaneers by 3.5 points, with a moneyline of -185 for Tampa Bay and +154 for Arizona. The over/under for the game is set at 48.5 points. Predictions from various analysts lean towards the Buccaneers, citing their need to bounce back after a series of losses and the Cardinals' ongoing struggles.

Official Statements & Responses

Cardinals head coach Jonathan Gannon acknowledged the challenges posed by injuries but emphasized the importance of adapting. “We have to be ready for both quarterbacks,” Gannon stated, referring to the uncertainty surrounding Mayfield's status. Buccaneers coach Todd Bowles expressed confidence in his team's ability to compete, regardless of who is under center.

Conclusion

As the Cardinals and Buccaneers prepare for their Week 13 showdown, both teams face critical challenges that could influence their playoff aspirations. The outcome of this game may hinge on the effectiveness of each team's quarterback and the ability to capitalize on defensive weaknesses. With playoff implications on the line, both teams will be looking to secure a much-needed victory.