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Moderate Exercise Boosts Mood via Adiponectin Release

11/29/2025

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Story summary
  • A single session of moderate exercise significantly boosts mood, attributed to adiponectin.
  • Adiponectin activates brain regions linked to emotional regulation, providing immediate relief from anxiety and depression.
  • Mood improved in both groups after testing 40 adults and mice.
  • Mice subjected to chronic stress showed enhanced behaviors after exercise, linked to increased adiponectin levels.
  • The study, published in Molecular Psychiatry, suggests exercise could treat depression and guide prescriptions.