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Genetic Mutations Linked to 15x Higher ADHD Risk

12/1/2025

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Story summary
  • Researchers identified rare genetic mutations in MAP1A, ANO8, and ANK2 that increase the risk of attention deficit hyperactivity disorder (ADHD) by as much as 15 times.
  • A study published in Nature by researchers from Aarhus University and the Broad Institute analyzed about 9,000 ADHD cases and 54,000 controls.
  • The findings show these genetic factors affect attention and impulse control.
  • The results may guide future treatments targeting ADHD's underlying causes.