Story perspectives

New Study Links Rapalink-1 to Extended Lifespan in Yeast

12/2/2025

Summary

Story summary

Researchers at Queen Mary University of London found that rapalink-1 extends the lifespan of fission yeast by regulating a metabolic feedback loop with agmatinases.
The study, published in Communications Biology, highlights the TOR pathway's role in growth and aging and suggests potential strategies combining TOR-targeting drugs with dietary or microbial interventions for healthy aging and cancer research.
Dr. Charalampos Rallis cautioned against agmatine supplements for longevity due to metabolic variability.

1 of 1

Story summary

Researchers at Queen Mary University of London found that rapalink-1 extends the lifespan of fission yeast by regulating a metabolic feedback loop with agmatinases.
The study, published in Communications Biology, highlights the TOR pathway's role in growth and aging and suggests potential strategies combining TOR-targeting drugs with dietary or microbial interventions for healthy aging and cancer research.
Dr. Charalampos Rallis cautioned against agmatine supplements for longevity due to metabolic variability.