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Light-Induced AR3 Gene Slashes Cancer Cell Survival

12/8/2025

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Story summary
  • Okayama University researchers demonstrated that Archaerhodopsin 3 (AR3) can induce apoptosis in cancer cells when exposed to green light.
  • They inserted AR3 genes into mouse colorectal and melanoma cancer cell lines and observed over 40% and 60% cell death, respectively, due to increased alkalinity.
  • In vivo tests showed tumors expressing AR3 were 65% to 75% smaller after laser exposure.