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New Breast Cancer Vaccine Shows Promise in Phase 1 Trials

12/12/2025

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Story summary
  • Cleveland Clinic researchers presented Phase 1 results of a vaccine targeting ?-lactalbumin to prevent triple-negative breast cancer at San Antonio Breast Cancer Symposium.
  • In 35 women, 74% developed an immune response and the vaccine showed only mild side effects.
  • Dr. G. Thomas Budd of Cleveland Clinic says the results are encouraging, but Phase 1 did not measure clinical effectiveness; Phase 2 is planned for late next year to reduce recurrence.