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MSU Creates Heart Organoids for Atrial Fibrillation Research

12/16/2025

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Story summary
  • Michigan State University (MSU) researchers developed the first human heart organoids that replicate atrial fibrillation.
  • The organoids, created from human stem cells, enable study of heart development, diseases, and drug responses affecting 60 million people.
  • Led by Aitor Aguirre at Michigan State University, the team showed inflammatory molecules caused irregular heartbeats.
  • The findings are published in Cell Stem Cell and address a 30-year gap in new A-fib treatments.