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Investigation Reveals Preventable Death of Disabled Man Due to Delayed Antibiotic Treatment

12/16/2025, 12:24:17 PM

Core Event: Delayed Treatment Leads to Fatal Sepsis

An investigation by the Parliamentary and Health Service Ombudsman (PHSO) has concluded that the death of a 45-year-old man, referred to as Graham, from sepsis was preventable due to a 34-hour delay in administering the correct intravenous (IV) antibiotics at Bassetlaw Hospital in Nottinghamshire. Graham, who suffered from Alexander's Disease, was admitted to the hospital in November 2022 with a urinary infection that was resistant to oral antibiotics.

Background & Context: Graham's Medical History

Graham had a history of frequent infections and required 24-hour care due to his condition, which affects the nervous system and causes developmental delays. His medical needs included a permanent catheter, making him particularly susceptible to urinary tract infections. Despite previous successful treatments with IV antibiotics, hospital staff opted to administer oral antibiotics during his final admission, disregarding advice from his mother, care home staff, and paramedics.

Investigation Findings: Communication Failures

The PHSO's investigation highlighted significant failures in communication and care. An email from Graham's GP recommending IV antibiotics went unseen, and despite verbal instructions, hospital staff delayed the administration of the appropriate medication. The report noted that Graham received an IV antibiotic only after 34 hours, and at half the required dosage. By the time a second dose was administered, Graham had developed sepsis and ultimately died a week later.

Official Statements & Responses

Sylvia, Graham's mother, expressed her distress over the care her son received, stating, "For 34 hours his care was non-existent... They had a duty of care to look after him." The chief executive of the PHSO, Rebecca Hilsenrath KC, remarked, "Losing a life through sepsis should not be an inevitability." In response, Karen Jessop, chief nurse at the Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust, acknowledged the incident, stating, "We are truly sorry for what happened in this case and for the loss experienced by the patient's family." She confirmed that immediate actions were taken to improve how antibiotics are prescribed and administered.

Criticism & Opposition: Family's Discontent

Despite receiving a written apology from the trust, Sylvia described it as "like a form letter" and noted that she had not seen any action plan that the trust was supposed to provide. This lack of transparency has raised concerns about accountability and the effectiveness of the measures implemented to prevent similar incidents in the future.

Conflicting Reports & Gaps

While the PHSO concluded that Graham's death was avoidable, the specifics of the hospital's internal review and the exact nature of the changes made to antibiotic protocols remain unclear. There is no detailed public account of the trust's action plan following the incident, which leaves questions about the long-term effectiveness of the changes.

Verbatim Quotes

“Losing a life through sepsis should not be an inevitability.” — Rebecca Hilsenrath KC, Chief Executive, PHSO

“We are truly sorry for what happened in this case and for the loss experienced by the patient's family.” — Karen Jessop, Chief Nurse, Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust