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Valacyclovir Linked to Faster Cognitive Decline in Alzheimer’s Study

12/17/2025

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Summary

Story summary

Columbia University researchers found that valacyclovir led to worse cognitive decline than placebo in a trial involving 120 participants.
The study tested valacyclovir for Alzheimer's disease linked to herpes infections to explore early intervention.
Experts say the viral hypothesis is not entirely dismissed.
Vaccination against viruses such as shingles could lower dementia risk.

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Story summary

Columbia University researchers found that valacyclovir led to worse cognitive decline than placebo in a trial involving 120 participants.
The study tested valacyclovir for Alzheimer's disease linked to herpes infections to explore early intervention.
Experts say the viral hypothesis is not entirely dismissed.
Vaccination against viruses such as shingles could lower dementia risk.