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Story perspectives

Controversial Puberty-Blocker Trial for Children Set to Begin

12/18/2025

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Story summary
  • Health Secretary Wes Streeting says children cannot consent to participate in a puberty-blocker trial and must have informed assent plus parental consent.
  • He says the trial is uncomfortable but necessary based on clinical advice from the Cass Review.
  • Trial involves over 220 children with gender dysphoria and begins in January to address evidence gaps.
  • Critics, including MP Dr. Caroline Johnson, raise concerns about ethics of puberty blockers on healthy children.