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Trump's Medicare Pilots to Slash Drug Costs in 2026

12/20/2025

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Story summary
  • On December 19, 2025, the U.S. government announced Medicare pilots, GUARD and GLOBE, to reduce out-of-pocket drug costs by benchmarking rebates to international prices, launching in 2026 and 2027.
  • President Donald Trump announced nine pharmaceutical companies will adopt a most-favored-nation pricing policy for Medicare and Medicaid.
  • Price reductions occurred for Amgen's Repatha and Gilead's Epclusa, dropping to $239 and $2,425 respectively.
  • He plans to negotiate with insurers to reduce costs.