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New H3N2 Variant Spreads, Threatens Vaccine Effectiveness

12/25/2025

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Story summary
  • The new influenza A H3N2 subclade K variant is spreading rapidly in the United States.
  • The World Health Organization notes the variant's evolution may limit this season's vaccine effectiveness.
  • The Centers for Disease Control and Prevention (CDC) reports nearly 4.6 million illnesses and 1,900 flu deaths this season.
  • Dr. Neil Maniar warns that lower vaccination rates could worsen the season.