Story perspectives
New Insights into Alzheimer's: Brain Tissue Study Unveils Synapse Loss
12/26/2025
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Story summary
- Dr. Claire Durrant and her University of Edinburgh team study brain tissue to understand why synapses are lost in Alzheimer's.
- They expose brain slices to toxic proteins to observe synapse destruction.
- Durrant notes lecanemab and donanemab have opened new possibilities, though their real-world impact remains limited.
- During a brain surgery observation, she collected a small piece of brain tissue for research.
