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Oprah Winfrey: Obesity Is a Disease, Not Failure

12/30/2025

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Summary

Story summary

Oprah Winfrey discusses her use of GLP-1 weight loss medication in a PEOPLE cover story, saying obesity is a disease, not a personal failure.
She will turn 72 in January.
The medication helps manage cravings and improve her relationship with food and exercise.
Her new book, co-authored with Dr. Ania M. Jastreboff, Enough: Your Health, Your Weight, is set for January 13.

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Story summary

Oprah Winfrey discusses her use of GLP-1 weight loss medication in a PEOPLE cover story, saying obesity is a disease, not a personal failure.
She will turn 72 in January.
The medication helps manage cravings and improve her relationship with food and exercise.
Her new book, co-authored with Dr. Ania M. Jastreboff, Enough: Your Health, Your Weight, is set for January 13.