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Oprah Winfrey Shares 50-Pound Weight Loss Journey

1/1/2026

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Story summary
  • Oprah Winfrey, 71, revealed her health journey in a recent PEOPLE cover story, highlighting her nearly 50-pound weight loss since starting GLP-1 medication two and a half years ago.
  • She has eliminated her desire for alcohol and now embraces a healthier lifestyle, exercising six days a week.
  • Winfrey stresses that obesity is a medical condition, encouraging others to seek help without shame.
  • Her new book, "Enough: Your Health, Your Weight and What It’s Like to Be Free," will be released on January 13, 2024.