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Story perspectives

CDC Considers Single-Dose HPV Vaccine Amid Controversy

1/8/2026

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Story summary
  • An independent vaccine advisory group will review the U.S. recommendation for a single-dose HPV vaccine, diverging from FDA-approved two- or three-dose regimens.
  • The CDC's change, influenced by Health and Human Services Secretary Robert F. Kennedy Jr. and U.S. President Donald Trump, bypassed the review process.
  • Merck, which manufactures Gardasil, warns that a single-dose regimen may be less effective.
  • The Vaccine Integrity Project is examining this and other vaccine recommendations.