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Chlorpyrifos Exposure Doubles Parkinson's Disease Risk, Study Finds

1/9/2026

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Story summary
  • A UCLA Health study links chlorpyrifos exposure to more than a 2.5-fold increase in Parkinson's disease risk.
  • Researchers analyzed data from 829 Parkinson's patients and 824 healthy individuals to assess chlorpyrifos exposure.
  • High exposure to chlorpyrifos from 10 to 20 years before diagnosis significantly raises risk.
  • The study shows chlorpyrifos damages dopamine-producing neurons.
  • It also disrupts autophagy, a cellular cleanup process.