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New Research Uncovers Why Chronic UTIs Persist in Girls

1/12/2026

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Story summary
  • Millions of women and girls worldwide suffer from chronic UTIs that resist treatment.
  • Researchers suggest bacteria embedded in the bladder wall may evade the immune system and antibiotics.
  • A case study of a 14-year-old girl showed Escherichia coli infections persisted despite aggressive antibiotics.
  • Arthika Manoharan of the University of Sydney aims to build a database on UTIs in children under 15 to identify why some infections become chronic.