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Blood Test Predicts Crohn's Disease Years Early

1/13/2026

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Summary

Story summary

A blood test measuring immune responses to flagellin can predict Crohn's disease years before symptoms appear.
Researchers at Sinai Health led the study on at-risk individuals.
Elevated responses occurred in more than a third of those who later developed Crohn's, especially among siblings.
The findings were published in Clinical Gastroenterology and Hepatology, suggesting the immune reaction may trigger Crohn's disease and enable earlier diagnosis.

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Story summary

A blood test measuring immune responses to flagellin can predict Crohn's disease years before symptoms appear.
Researchers at Sinai Health led the study on at-risk individuals.
Elevated responses occurred in more than a third of those who later developed Crohn's, especially among siblings.
The findings were published in Clinical Gastroenterology and Hepatology, suggesting the immune reaction may trigger Crohn's disease and enable earlier diagnosis.