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NFL Divisional Round Preview: Key Matchups and Predictions

1/15/2026, 11:16:50 PM

Denver Broncos vs. Buffalo Bills

The top-seeded Denver Broncos (14-3) will host the sixth-seeded Buffalo Bills (12-5) at Empower Field at Mile High on January 17. The Broncos, coming off a bye week, are slight favorites, despite being underdogs in the betting market. Denver's defense, which led the NFL with 68 sacks, will be crucial in containing Bills quarterback Josh Allen, who has been battling injuries but remains a formidable threat.

The Broncos' offense, led by quarterback Bo Nix, aims to exploit a banged-up Bills secondary missing key players like Gabe Davis and Tyrell Shavers. Nix's ability to connect with emerging receivers like Troy Franklin and Courtland Sutton will be pivotal. The Broncos' success hinges on their ability to establish the run and protect Nix against a Bills defense that has shown vulnerability.

Houston Texans vs. New England Patriots

The Houston Texans (12-5) will face the New England Patriots (15-3) at Gillette Stadium on January 18. The Texans, riding a ten-game winning streak, boast one of the league's top defenses, which was instrumental in their wild-card victory over the Pittsburgh Steelers. However, quarterback C.J. Stroud's struggles with turnovers could be a liability against a disciplined Patriots defense that effectively pressured Justin Herbert in their previous playoff game.

The Texans will need a strong performance from their running game, featuring Woody Marks and Nick Chubb, to alleviate pressure on Stroud. Meanwhile, the Patriots, led by quarterback Drake Maye, will look to exploit any weaknesses in the Texans' secondary, especially if top receiver Nico Collins is unavailable due to injury.

Seattle Seahawks vs. San Francisco 49ers

In the NFC, the Seattle Seahawks (14-3) will host the San Francisco 49ers (12-5) on January 17. The Seahawks, fresh off a division title, are favored to win, having recently defeated the 49ers 13-3 in Week 18. Seattle's defense, ranked first in points allowed, will be tested against a resilient 49ers offense led by quarterback Brock Purdy.

The 49ers will need to adapt their game plan following the loss of tight end George Kittle to injury. The matchup will hinge on the effectiveness of San Francisco's offensive line in protecting Purdy against a formidable Seahawks pass rush.

Los Angeles Rams vs. Chicago Bears

The Los Angeles Rams (13-5) will travel to face the Chicago Bears (12-6) on January 18. The Rams, led by quarterback Matthew Stafford, are looking to build on their wild-card win against the Carolina Panthers. Chicago's defense, known for its ability to create turnovers, will be a significant challenge for the Rams, who must avoid mistakes in the frigid conditions expected at Soldier Field.

The Bears, known for their comeback victories, will rely on quarterback Caleb Williams to continue his impressive play. The outcome may depend on whether the Rams can contain Williams' mobility and limit explosive plays.

Conclusion

As the NFL Divisional Round approaches, each matchup presents unique challenges and opportunities. The outcomes will likely hinge on quarterback performances, defensive strategies, and the ability to capitalize on turnovers. Fans can expect thrilling football as teams battle for a chance to advance to the conference championships.