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Jamie-Lynn Sigler Shines as MS Warrior on Grey's Anatomy

1/16/2026

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Story summary
  • Jamie-Lynn Sigler, the actress diagnosed with multiple sclerosis in 2002, portrays Dr. Laura Kaplan, a urologist with MS, in Grey’s Anatomy.
  • She described the emotional impact of saying “I have MS” on camera and feared it would end her acting career.
  • Sigler aims to authentically represent living with MS, emphasizing strength and resilience.
  • Grey’s Anatomy airs Thursdays at 10 p.m. ET on ABC.