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Study Reveals Super Agers' Genetic Resilience to Alzheimer's

1/26/2026

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Summary

Story summary

A Vanderbilt University Medical Center study on late-onset Alzheimer's disease finds super agers aged 80 and older are 68% less likely to carry the APOE-?4 variant and 28% more likely to have the APOE-?2 variant.
The analysis used data from 18,080 participants, making it the largest study of its kind.
The researchers aim to enhance understanding of resilience against Alzheimer's disease.

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Story summary

A Vanderbilt University Medical Center study on late-onset Alzheimer's disease finds super agers aged 80 and older are 68% less likely to carry the APOE-?4 variant and 28% more likely to have the APOE-?2 variant.
The analysis used data from 18,080 participants, making it the largest study of its kind.
The researchers aim to enhance understanding of resilience against Alzheimer's disease.