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Menopause Linked to Alzheimer's-Like Brain Changes, Study Finds

1/27/2026

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Summary

Story summary

A UK study links menopause to brain changes resembling those seen in Alzheimer's disease, implying higher dementia risk.
The study involved nearly 125,000 women, with about 11,000 undergoing magnetic resonance imaging (MRI) scans, and was published in Psychological Medicine.
Hormone replacement therapy did not prevent grey matter loss.
Women on HRT showed poorer mental health, possibly due to pre-existing conditions.

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Story summary

A UK study links menopause to brain changes resembling those seen in Alzheimer's disease, implying higher dementia risk.
The study involved nearly 125,000 women, with about 11,000 undergoing magnetic resonance imaging (MRI) scans, and was published in Psychological Medicine.
Hormone replacement therapy did not prevent grey matter loss.
Women on HRT showed poorer mental health, possibly due to pre-existing conditions.