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South Carolina Sees Largest Measles Outbreak in 20 Years

1/28/2026

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Story summary
  • South Carolina's measles outbreak has reached 789 cases, the largest since the virus was eliminated in the U.S. over 20 years ago.
  • The state health department confirmed 89 new cases since Friday, with 18 individuals hospitalized but no fatalities reported.
  • Exposures occurred at three additional schools in Spartanburg County, adding to quarantines at 20 other schools.
  • Among the 729 infected individuals with known vaccination status, 695 were unvaccinated.
  • The outbreak raises concerns about the potential loss of the U.S.'s measles elimination status during a review by the Pan American Health Organization in April 2024.