Story perspectives

Testosterone Therapy Linked to Higher Acne Risk in Transmasculine Individuals

1/31/2026

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Summary

Story summary

The American Medical Journal reports testosterone therapy raises acne risk for transmasculine individuals, peaking in the first year.
The study analyzed nearly 281,000 individuals, including over 20,000 trans patients.
It found 15.8% of transmasculine individuals developed acne after five years, versus 3.8% in cis men and 10.5% in cis women.
Transfeminine individuals on estradiol showed 6.0% acne incidence, higher than cis men, prompting proactive management.

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Story summary

The American Medical Journal reports testosterone therapy raises acne risk for transmasculine individuals, peaking in the first year.
The study analyzed nearly 281,000 individuals, including over 20,000 trans patients.
It found 15.8% of transmasculine individuals developed acne after five years, versus 3.8% in cis men and 10.5% in cis women.
Transfeminine individuals on estradiol showed 6.0% acne incidence, higher than cis men, prompting proactive management.