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Ketogenic Diet Linked to Liver Issues in Mice

2/1/2026

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Summary

Story summary

University of Utah Health researchers report that a long-term ketogenic diet may cause serious health issues in mice.
In the study, mice on this high-fat, low-carbohydrate diet gained less weight but developed fatty liver disease and impaired glucose regulation.
Male mice showed more severe liver issues than females.
Lead author Molly Gallop cautioned that mouse findings may not apply to humans and urged consulting healthcare providers before starting such diets.

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Story summary

University of Utah Health researchers report that a long-term ketogenic diet may cause serious health issues in mice.
In the study, mice on this high-fat, low-carbohydrate diet gained less weight but developed fatty liver disease and impaired glucose regulation.
Male mice showed more severe liver issues than females.
Lead author Molly Gallop cautioned that mouse findings may not apply to humans and urged consulting healthcare providers before starting such diets.