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Researchers Identify PEDS1 Gene Linked to Developmental Delays

2/6/2026

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Summary

Story summary

A research team from the Hebrew University of Jerusalem and INSERM in France identified the gene PEDS1 linked to a severe neurodevelopmental disorder in children.
Using CRISPR, they disrupted about 20,000 genes to study brain development.
The study found that mutations in PEDS1 cause developmental delays and reduced brain size.
The findings were confirmed in a mouse model, with access provided via an online database.

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Story summary

A research team from the Hebrew University of Jerusalem and INSERM in France identified the gene PEDS1 linked to a severe neurodevelopmental disorder in children.
Using CRISPR, they disrupted about 20,000 genes to study brain development.
The study found that mutations in PEDS1 cause developmental delays and reduced brain size.
The findings were confirmed in a mouse model, with access provided via an online database.