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Study Links Maternal Genes to Pregnancy Loss Risks

2/15/2026

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Story summary
  • A new study links maternal gene variants to chromosomal abnormalities that cause pregnancy loss.
  • Researchers analyzed data from over 139,000 in vitro fertilization embryos and found associations between maternal variants and aneuploid embryos.
  • Key genes identified include SMC1B and C14orf39, involved in chromosome stability and crossover recombination.
  • The findings are not yet applicable to patient care, but recombination errors may raise aneuploidy risk and infertility.