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Ancient Regeneration Insights from Fish and Amphibians

2/18/2026

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Story summary
  • A Nature Communications study led by Igor Schneider at Louisiana State University finds immune cells and nucleated red blood cells rush to wound sites after amputation in the Senegal bichir, axolotl, and zebrafish.
  • The nucleated red blood cells may provide instructive signals for regeneration.
  • The study suggests regeneration mechanisms are ancient and shared among these species, despite about 400 million years of divergence.