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Justice Department Clears Cassava, Shifts Focus to Epilepsy

2/19/2026

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Story summary
  • On February 19, 2026, Cassava Sciences announced that the United States Department of Justice has concluded its investigation into simufilam research misconduct.
  • The indictment against Hoau-Yan Wang, former adviser, has been dismissed.
  • Cassava halted Alzheimer's development of simufilam last year due to poor trial results.
  • The company is now shifting its focus to developing simufilam for tuberous sclerosis complex-related epilepsy.