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Isomorphic Labs Unveils IsoDDE: Revolutionary AI for Drug Discovery

2/20/2026

Summary

Story summary

Isomorphic Labs in London introduced IsoDDE, a powerful AI model for predicting drug–protein interactions.
The release follows AlphaFold3 from Google DeepMind, underscoring rapid AI progress in drug discovery.
IsoDDE remains proprietary, limiting access to its underlying methodologies.
Mohammed AlQuraishi, a computational biologist, praised IsoDDE for predicting interactions beyond its training data.
The model reportedly outperforms existing methods, including Boltz-2, in determining binding affinity.

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Story summary

Isomorphic Labs in London introduced IsoDDE, a powerful AI model for predicting drug–protein interactions.
The release follows AlphaFold3 from Google DeepMind, underscoring rapid AI progress in drug discovery.
IsoDDE remains proprietary, limiting access to its underlying methodologies.
Mohammed AlQuraishi, a computational biologist, praised IsoDDE for predicting interactions beyond its training data.
The model reportedly outperforms existing methods, including Boltz-2, in determining binding affinity.