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Puberty Blockers Trial Paused Over Age and Safety Concerns

2/21/2026

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Story summary
  • The Medicines and Healthcare products Regulatory Agency (MHRA) paused a puberty blockers trial after recommending a minimum age of 14 because of long-term risks.
  • Discussions between the MHRA and King’s College London will address wellbeing concerns.
  • The trial aimed to recruit about 226 participants aged 10–16 and followed the Cass review.
  • Health Secretary Wes Streeting urged following expert advice, while Conservative leader Kemi Badenoch called for halting the trial.