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Christina Applegate Opens Up About MS and Motherhood

2/25/2026

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Summary

Story summary

Christina Applegate, actress, reveals a 2021 multiple sclerosis diagnosis and its impact in her memoir You With the Sad Eyes, releasing March 3.
She reflects on a painful childhood, abusive relationships, and fame amid illness.
She emphasizes honesty, saying her life isn't wrapped in a bow and f***ing sucks.
Despite challenges, she cherishes motherhood to her 15-year-old daughter Sadie and drives her to school.

History

Historical Context

Founded in 1946 by Sylvia Lawry in New York City, the National Multiple Sclerosis Society (NMSS) aims to support those affected by multiple sclerosis (MS) and fund research for a cure. With over 2.3 million diagnosed globally, the NMSS has significantly influenced public awareness and advocacy, as highlighted by Christina Applegate's memoir, which underscores the ongoing challenges faced by individuals with chronic conditions.

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Story summary

Christina Applegate, actress, reveals a 2021 multiple sclerosis diagnosis and its impact in her memoir You With the Sad Eyes, releasing March 3.
She reflects on a painful childhood, abusive relationships, and fame amid illness.
She emphasizes honesty, saying her life isn't wrapped in a bow and f***ing sucks.
Despite challenges, she cherishes motherhood to her 15-year-old daughter Sadie and drives her to school.

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