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Super-Agers Generate Double Neurons, Stay Sharp into 90s

2/27/2026

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Story summary
  • New research from the University of Illinois College of Medicine shows that older adults labeled 'super-agers' generate twice as many new neurons in the hippocampus as typical older adults.
  • The study, published in Nature, notes that super-agers keep cognitive sharpness into their 80s and 90s and exhibit a distinct 'resilience signature' in the brain.
  • Researchers acknowledge study limitations but say the findings highlight the role of cognitive engagement and physical activity for brain health.