Story perspectives

Testosterone Therapy Post-Knee Surgery Linked to Serious Risks

3/5/2026

Summary

Story summary

A study presented at the American Academy of Orthopaedic Surgeons links testosterone therapy within one year of knee replacement to higher risks of infection, blood clots, kidney damage, and knee instability.
The study followed over 13,000 patients and reported higher complication rates shortly after surgery up to five years.
The findings are preliminary until published in a peer-reviewed journal.
Researchers urge further study of testosterone’s impact on bone healing.

1 of 1

Story summary

A study presented at the American Academy of Orthopaedic Surgeons links testosterone therapy within one year of knee replacement to higher risks of infection, blood clots, kidney damage, and knee instability.
The study followed over 13,000 patients and reported higher complication rates shortly after surgery up to five years.
The findings are preliminary until published in a peer-reviewed journal.
Researchers urge further study of testosterone’s impact on bone healing.