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Roche's Petrelintide Shows Mixed Results in Trials

3/6/2026

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Story summary
  • Citi analysts say petrelintide, developed by Roche Holding and Zealand Pharma, may perform better in combination with Roche's CT-388 than alone.
  • A midstage trial showed petrelintide's efficacy was underwhelming and its tolerability resembled placebo.
  • A late-stage monotherapy study is planned to begin in the second half of the year.
  • A midstage trial for the combination therapy is planned as well.