Story perspectives

Study Reveals Two ADHD Brain Subtypes for Tailored Treatment

3/6/2026

Summary

Story summary

The study identifies two distinct structural brain subtypes of ADHD with different gray matter patterns.
Researchers analyzed MRI data from 135 diagnosed children and 182 neurotypical youths.
One subtype shows increased gray matter in the frontal regions and cerebellum and is linked to inattention.
The second subtype shows gray matter atrophy and hyperactivity/impulsivity.
The study, published in General Psychiatry, suggests personalized treatment strategies could improve ADHD management.

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Story summary

The study identifies two distinct structural brain subtypes of ADHD with different gray matter patterns.
Researchers analyzed MRI data from 135 diagnosed children and 182 neurotypical youths.
One subtype shows increased gray matter in the frontal regions and cerebellum and is linked to inattention.
The second subtype shows gray matter atrophy and hyperactivity/impulsivity.
The study, published in General Psychiatry, suggests personalized treatment strategies could improve ADHD management.