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Appendix: Immune Ally and Evolutionary Key to Health

3/9/2026

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Story summary
  • The appendix supports the immune system and helps maintain gut microbiome stability.
  • In early life, it aids immune cell development and may shelter beneficial bacteria.
  • Modern sanitation has diminished its importance.
  • Appendicitis remains a risk, but appendectomy does not adversely affect fertility.
  • Understanding the appendix's evolutionary history can inform contemporary medical practices.