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Roche Shares Dip 7.5% as Giredestrant Trial Fails

3/9/2026

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Roche's Drug Setback
  • Roche Holding AG reported that giredestrant failed to meet the primary endpoint in a late-stage study, and its shares fell about 7.5%.
  • The trial showed no significant difference in disease progression between giredestrant and standard therapy.
  • Roche remains optimistic, citing prior studies indicating potential benefits.
  • Roche will continue development with a trial expected to report results in 2027.
  • Analysts say the drug could still have commercial potential despite recent disappointments.