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High Anticholinergic Use Linked to 71% Heart Risk

3/10/2026

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Story summary
  • A study published in BMC Medicine found that high anticholinergic use is linked to a 71% higher risk of heart problems.
  • The study followed more than 500,000 Stockholm residents aged 45 and older for up to 14 years.
  • Hong Xu, a senior researcher, cautions that the results do not prove causation.
  • Clinical trials are needed to determine whether these drugs directly affect heart health.