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New Insights Reveal Dynamic Nature of Nuclear Pore Complexes

3/10/2026

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Story summary
  • Nuclear pore complexes (NPCs) regulate molecular traffic in and out of the nucleus.
  • NPCs consist of hundreds of proteins and are found in nearly every eukaryotic cell.
  • The central barrier of NPCs is dynamic, moving and morphing, which complicates visualization.
  • High-resolution microscopy shows this flexibility, revealing that NPC function relies on rearrangement.
  • This research enhances understanding of cellular processes essential for life.