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Yale Study Uncovers CoA Transport Mechanism in Mitochondria

3/12/2026

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Summary

Story summary

Yale researchers have revealed how coenzyme A (CoA) is transported into mitochondria, enabling its role in metabolism.
The study, published in Nature Metabolism, identifies cellular mechanisms that facilitate CoA transport.
Researchers identified 33 CoA conjugates in cells, 23 of which are located in mitochondria.
This understanding could lead to new treatments for diseases linked to CoA dysfunction.

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Story summary

Yale researchers have revealed how coenzyme A (CoA) is transported into mitochondria, enabling its role in metabolism.
The study, published in Nature Metabolism, identifies cellular mechanisms that facilitate CoA transport.
Researchers identified 33 CoA conjugates in cells, 23 of which are located in mitochondria.
This understanding could lead to new treatments for diseases linked to CoA dysfunction.