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Genetics Influences Half of Lifespan, Study Reveals

3/17/2026

Center

Researchers Uncover Lifespan Genetics

Researchers from the Weizmann Institute of Science find genetics account for 50% of human lifespan.
They analyzed twin registries in Sweden and Denmark to separate genetic influences from extrinsic mortality.
The finding could reshape aging research and public health.
The VITAL-H trial at UT Health San Antonio will test rapamycin, semaglutide, and dapagliflozin for aging, with $38 million in federal support and 1,000 South Texas participants focusing on health span.

Left

Giri Identifies OTUD3 Gene

Dr. Rabina Giri of Mater Hospital in South Brisbane led researchers who identified the OTUD3 gene linked to ulcerative colitis across three generations.
The OTUD3 gene is crucial for gut lining integrity, and its mutation appeared in many ulcerative colitis patients.
Giri emphasized therapies targeting the gut barrier rather than the immune system.
The findings were published in Cellular and Molecular Gastroenterology and Hepatology, calling for further research.

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Researchers Uncover Lifespan Genetics

Researchers from the Weizmann Institute of Science find genetics account for 50% of human lifespan.
They analyzed twin registries in Sweden and Denmark to separate genetic influences from extrinsic mortality.
The finding could reshape aging research and public health.
The VITAL-H trial at UT Health San Antonio will test rapamycin, semaglutide, and dapagliflozin for aging, with $38 million in federal support and 1,000 South Texas participants focusing on health span.

1 / 2