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Chlorpyrifos Exposure Linked to Increased Parkinson's Risk

3/17/2026

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Story summary
  • A UCLA Health study links long-term chlorpyrifos exposure to a higher risk of Parkinson's disease.
  • Residents in areas with ongoing exposure have over 2.5 times the likelihood of developing the condition.
  • The research combined human data with lab experiments showing that chlorpyrifos damages dopamine-producing neurons and disrupts autophagy.
  • The findings designate chlorpyrifos as a risk factor and suggest future autophagy-targeted therapies.