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FDA Approves Icotyde: Game-Changer for Plaque Psoriasis Treatment

3/18/2026

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Story summary
  • The FDA approved Johnson & Johnson's Icotyde, an oral pill, to treat moderate-to-severe plaque psoriasis in adults and children 12 and older.
  • Icotyde offers a once-daily regimen, a first-of-its-kind treatment.
  • Analysts project Icotyde could reach over $8 billion in peak sales as it competes with Bristol Myers Squibb's Sotyktu and AbbVie's Skyrizi.
  • Icotyde blocks interleukin-23 (IL-23), the inflammation-related protein, and is being studied for ulcerative colitis and Crohn's disease.