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Johnson & Johnson's Icotyde: A Game-Changer for Psoriasis Treatment

3/19/2026

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Story summary
  • Johnson & Johnson announced that the U.S. FDA approved Icotyde, a once-daily oral pill for moderate to severe plaque psoriasis.
  • Icotyde is the first oral treatment to compete with injectable therapies such as Tremfya and Skyrizi.
  • The drug targets the IL-23 receptor.
  • Analysts project Icotyde could exceed $8 billion in annual sales due to its safety and effectiveness.
  • Johnson & Johnson is exploring Icotyde for other autoimmune conditions, including psoriatic arthritis and Crohn's disease.