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Today in History: Zidovudine becomes first FDA-approved HIV/AIDS treatment

3/20/2026

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Story summary
  • On March 20, 1987, the U.S. Food and Drug Administration approved zidovudine (AZT) as the first antiretroviral treatment for HIV/AIDS. This landmark decision marked a significant advancement in managing the virus, allowing patients to suppress viral loads and improve life expectancy. Zidovudine remains a crucial component in HIV treatment regimens today.