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Story summary
- Fudan University researchers find that psychological stress worsens eczema by activating prodynorphin-positive (Pdyn+) sympathetic neurons that connect the brain to the skin and trigger eosinophils via the CCL11-CCR3 pathway.
- Fudan University researchers analyzed data from 51 eczema patients and mouse models to identify these mechanisms.
- Increased stress links to higher eosinophil levels in the skin.
- Science published the findings, and the report suggests stress management could improve eczema treatments.
